爱必信现货—雷帕霉素Rapamycin,速来抢购吧!!!

2015-08-10 13:43 · absinbio

(RAPA)是一种新型大环内酯类免疫抑制剂。雷帕霉素通过不同的细胞因子受体阻断信号传导,阻断T淋巴细胞及其他细胞由G1期至S期的进程,从而发挥免疫抑制效应。

 

爱必信现货—雷帕霉素Rapamycin,速来抢购吧!!!

 

 

化学名:23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine

CAS No:53123-88-9

分子式:C51H79NO13

分子量:914.17

纯度:> 99%

溶解度:Soluble to 20 mM in ethanol and to 50 mM in DMSO

保存: -20 ºC

产品货号
品名
规格
价格
货期
abs810030a
Rapamycin
5mg
300元  
现货
abs810030b
Rapamycin
10mg
450元
现货
abs810030c
Rapamycin
25mg
700元
现货
abs810030d
Rapamycin
50mg
1000元
现货
abs810030e
Rapamycin
100mg
1400元
现货

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产品描述:

Rapamycin is a macrocyclic triene antibioticpossessing potent immunosuppressant and anticancer activity.

It forms a complex with FKBP12 that binds toand inhibits the molecular target of rapamycin (mTOR).

mTOR is a member of the phosphoinositidekinase-related kinase (PIKK) family that enhances cellular

proliferation via the phosphoinositol3-kinase/Akt signaling pathway. Inhibition of this pathway by rapamycin

blocks downstream elements that result incell cycle arrest in G1. The effectors of mTOR action include

4EBP1 and S6K1..

 

Research Use only 仅限试验室研究用

 

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