Nature子刊:远紫外线可杀死流感病毒,且不伤害人体
2018/02/15
流感高发季节,病毒来势汹汹,防不胜防。最近,哥伦比亚大学一项研究表明,持续低剂量的远紫外线(UVC)光可以杀死空气中的流感病毒,而不会伤害人体组织。也就是说,在医院、医生办公室、学校、机场、飞机等公共场所使用远紫外线灯,可以对季节性流感流行以及流感大流行做出强有力的检查。


流感病毒主要通过细小的液滴或气溶胶在人与人之间传播,当流感患者咳嗽,打喷嚏或说话时,流感病毒就会传播。哥伦比亚大学欧文医学中心(CUIMC)放射学研究中心的这项研究,目的就是测试远紫外线灯是否可以有效地杀死公共场所空气中的悬浮的流感病毒。相关成果发表在《Scientific Reports》杂志上。

几十年来,科学家们已经了解到,广谱性紫外线(波长为200-400纳米),可以通过破坏将DNA结合在一起的分子键来杀死细菌和病毒,而且非常有效。研究负责人David J. Brenner博士说:“不幸的是,传统的杀菌紫外线对人类健康也有害,可能会导致皮肤癌和白内障,从而阻碍其在公共场所的使用。”

“远紫外线的光线范围非常有限,无法穿透人体皮肤的外层死皮细胞层或眼睛的泪液层,因此不会对人类健康造成危害。但是由于病毒和细菌远小于人类细胞,远紫外线可以达到它们的DNA并将其杀死。”他说。


DOI:10.1038/s41598-018-21058-w

通过之前的研究,Brenner博士的研究小组已经证明,远紫外线光能有效杀死MRSA(耐甲氧西林金黄色葡萄球菌)细菌,这是外科手术伤口感染的常见原因,且不伤害人类或小鼠皮肤。

在这项研究中, H1N1病毒(一种常见的流感病毒株)被释放到实验室中,并暴露于非常低剂量的222nm 远紫外线光下。结果发现,与对照组相比,远紫外线光有效地灭活了流感病毒,其效率与传统的杀菌紫外线光的效率大致相同。

“如果我们的结果在其他环境中得到证实,那么在公共场所使用低水平远紫外线灯将是一种安全有效的方法,用于限制流感和结核病等由空气传播的微生物疾病。Brenner博士说道。“而与流感疫苗不同的是,远紫外线可能对所有的空气微生物,甚至是新出现的菌株都有效。”

参考资料

Special UV light safely kills airborne flu virus, finds study

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  • Far-UVC light: A new tool to control the spread of airborne-mediated microbial diseases

    Airborne-mediated microbial diseases such as influenza and tuberculosis represent major public health challenges. A direct approach to prevent airborne transmission is inactivation of airborne pathogens, and the airborne antimicrobial potential of UVC ultraviolet light has long been established; however, its widespread use in public settings is limited because conventional UVC light sources are both carcinogenic and cataractogenic. By contrast, we have previously shown that far-UVC light (207–222 nm) efficiently inactivates bacteria without harm to exposed mammalian skin. This is because, due to its strong absorbance in biological materials, far-UVC light cannot penetrate even the outer (non living) layers of human skin or eye; however, because bacteria and viruses are of micrometer or smaller dimensions, far-UVC can penetrate and inactivate them. We show for the first time that far-UVC efficiently inactivates airborne aerosolized viruses, with a very low dose of 2 mJ/cm2 of 222-nm light inactivating >95% of aerosolized H1N1 influenza virus. Continuous very low dose-rate far-UVC light in indoor public locations is a promising, safe and inexpensive tool to reduce the spread of airborne-mediated microbial diseases.

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