多学一门语言,有助于延缓痴呆患者认知障碍
2018/02/10
数十年研究已经表明,多掌握一门语言有助于改善大脑功能。现在,一项新研究揭示,这一技能对于阿尔兹海默症(AD)以及轻度认知障碍(MCI)患者的大脑也有积极影响。


图片来源:Concordia University

这一发表在《Neuropsychologia》期刊的研究成果进一步证实了‘掌握两种语言有利于增加大脑皮质厚度、灰质密度’的假说。

“之前关于语言与大脑关联的研究都建立在健康群体。”来自于康考迪亚大学的心理学教授Natalie Phillips解释道。现在,他带领团队转变思路,以AD、MCI患者为模型,发现语言对于大脑结构的影响。


图片来源:Neuropsychologia(doi.org/10.1016/j.neuropsychologia.2017.12.036)

Natalie Phillips团队首次使用高分辨率、全脑MRI数据,并借助复杂的分析技术测量特定大脑区域的皮质厚度、组织密度。他们共分析了68名MCI患者(其中有34名会多种语言)、26名AD患者(其中13名会多种语言),重点关注的大脑区域包括:与语言、认知相关的额叶区域、与记忆有关的内侧颞叶区域,以及患者因为病情而萎缩的大脑区域。

结果发现,相比于只会一种语言的人而言,掌握多种语言的患者大脑的皮质厚度更厚。这意味着,认知及记忆能力更强。

Natalie Phillips认为,这些结果表明,会一种以上语言有助于提高认知能力。掌握多种语言与大脑可塑性有关,有望延缓因大脑萎缩而导致的认知障碍。

参考资料:

Bilingualism could offset brain changes in Alzheimer's

所有文章仅代表作者观点,不代表本站立场。如若转载请联系原作者。
查看更多
  • Structural brain differences between monolingual and multilingual patients with mild cognitive impairment and Alzheimer disease: Evidence for cognitive reserve

    Two independent lines of research provide evidence that speaking more than one language may 1) contribute to increased grey matter in healthy younger and older adults and 2) delay cognitive symptoms in mild cognitive impairment (MCI) or Alzheimer disease (AD). We examined cortical thickness and tissue density in monolingual and multilingual MCI and AD patients matched (within Diagnosis Groups) on demographic and cognitive variables. In medial temporal disease-related (DR) areas, we found higher tissue density in multilingual MCIs versus monolingual MCIs, but similar or lower tissue density in multilingual AD versus monolingual AD, a pattern consistent with cognitive reserve in AD. In areas related to language and cognitive control (LCC), both multilingual MCI and AD patients had thicker cortex than the monolinguals. Results were largely replicated in our native-born Canadian MCI participants, ruling out immigration as a potential confound. Finally, multilingual patients showed a correlation between cortical thickness in LCC regions and performance on episodic memory tasks. Given that multilinguals and monolinguals were matched on memory functioning, this suggests that increased gray matter in these regions may provide support to memory functioning. Our results suggest that being multilingual may contribute to increased gray matter in LCC areas and may also delay the cognitive effects of disease-related atrophy.

    展开 收起
发表评论 我在frontend\modules\comment\widgets\views\文件夹下面 test