JNCI:每天饮用苏打水≥2杯,癌症风险高79%
2016/07/24
日前,发表在《Journal of the National Cancer Institute》杂志上的研究表明,大量饮用含糖饮料如苏打水和果汁会增加胆囊癌的风险。


日前,发表在《Journal of the National Cancer Institute》杂志上的研究表明,大量饮用含糖饮料如苏打水和果汁会增加胆囊癌的风险。

该研究由瑞典卡罗林斯卡研究所的专家开展,为了探索苏打水和癌症风险之间的关系,他们分析了70000名成年人的饮食习惯调查数据,并对这些人进行了13年的随访调查,以了解他们的癌症诊断情况。

这些参与者在1997年完成了饮食问卷调查,包括回答在过去一周以及一年里消耗了多少苏打水或果汁饮料,参与者的平均年龄为61岁,大约有一半的人属于超重,25%是吸烟者,研究人员排除了过往被诊断出癌症或糖尿病的志愿者。

研究结果发现,与那些完全不接触含糖饮料的人相比,每天至少饮用两杯果汁或碳酸饮料的人患胆囊肿瘤的风险增加2倍以上,患肝胆管癌的风险高79%。他们也更容易超重,更倾向于食用高热量、高糖低蛋白的食物。

该研究提供证据表明肥胖和血糖水平升高增加了这类恶性肿瘤的风险,含糖饮料在推动这种风险中发挥了重要的作用。

然而,由于该试验属于观察性研究,结果并不能直接证明汽水和含糖饮料会导致癌症。这可能是由于研究人员只收集了饮品习惯的数据,最终结果可能还受参与者本身的变化所影响。

未参与该项目的研究人员,德克萨斯大学西南医学院Margo Denke博士说,“该研究还缺乏准确的数据来评估参与者饮用含糖饮料时选择苏打水的频率。”

相关链接:

Could soda and fruit juice give you cancer? Sugary drinks 'double risk of disease'

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  • Sweetened Beverage Consumption and Risk of Biliary Tract and Gallbladder Cancer in a Prospective Study

    Background: Sugar-sweetened beverage consumption raises blood glucose concentration and has been positively associated with weight gain and type 2 diabetes, all of which have been implicated in the development of biliary tract cancer (BTC). This study examined the hypothesis that sweetened beverage consumption is positively associated with risk of BTC in a prospective study. Methods: The study population comprised 70 832 Swedish adults (55.9% men, age 45-83 years) from the Swedish Mammography Cohort and Cohort of Swedish Men who were free of cancer and diabetes and completed a food frequency questionnaire at baseline. Incident BTC case patients were ascertained through linkage with the Swedish Cancer Register. Cox proportional hazards regression model was used to analyze the data. All statistical tests were two-sided. Results: During a mean follow-up of 13.4 years, 127 extrahepatic BTC case patients (including 71 gallbladder cancers) and 21 intrahepatic BTC case patients were ascertained. After adjustment for other risk factors, women and men in the highest category of combined sugar-sweetened and artificially sweetened beverage consumption had a statistically significantly increased risk of extrahepatic BTC and gallbladder cancer. The multivariable hazard ratios for two or more servings per day (200 mL/serving) of sweetened beverages compared with no consumption were 1.79 (95% confidence interval [CI] = 1.02 to 3.13) for extrahepatic BTC and 2.24 (95% CI = 1.02 to 4.89) for gallbladder cancer. The corresponding hazard ratio for intrahepatic BTC was 1.69 (95% CI = 0.41 to 7.03). Conclusions: These findings support the hypothesis that high consumption of sweetened beverages may increase the risk of BTC, particularly gallbladder cancer.

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