英国研究称常吃西红柿可防前列腺癌
新华网 · 2014/08/31
近日,英国一项最新研究发现,常吃西红柿及相关制品可显著降低前列腺癌风险。专家还指出,每天吃多种果蔬、坚持适量运动,都是防癌良方。


饮食和生活习惯对前列腺癌发病率有重要影响。英国一项最新研究发现,常吃西红柿及相关制品可显著降低此类癌症风险。专家还指出,每天吃多种果蔬、坚持适量运动,都是防癌良方。

前列腺癌是全球男性第二大癌症杀手,仅英国每年就新增约3.5万病例。此前研究发现,发达国家前列腺癌发病率较高,可能与“西式”饮食及生活习惯有关。

英国布里斯托尔大学、牛津大学等机构的研究人员考察了近2万名英国男性的饮食和生活习惯,他们的年龄在50至59岁之间,其中约1800人患有前列腺癌。

研究结果发现,将吸烟、运动习惯等因素考虑进去,多吃西红柿防癌效果最为明显。一周摄取西红柿或西红柿汁等超过10次,每次不低于80克,可将前列腺癌风险降低约18%。如果遵循英国卫生部门的健康建议,即每天摄入的水果蔬菜不少于5种,每种不低于80克,则前列腺癌患病风险也可降低约24%。

研究人员认为,这可能是西红柿中大量的抗氧化剂“番茄红素”起到了作用。这种物质可对抗人体中的毒素,使细胞免于受损。多吃西红柿有助于预防前列腺癌,不过除了西红柿,还应该摄取多种果蔬,并且适当锻炼、保持体重,这些都有助于预防癌症。

这一研究的相关论文已发表在美国新一期《癌症流行病学、生物标志和预防》杂志上。

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  • Adherence to dietary and lifestyle recommendations and prostate cancer risk in the Prostate Testing for Cancer and Treatment (ProtecT) trial

    Background: The World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) published eight recommendations for cancer prevention but they are not targeted at prostate cancer prevention. We investigated whether adherence to the WCRF/AICR recommendations and a prostate cancer dietary index are associated with prostate cancer risk. Methods: We conducted a nested case-control study of 1,806 PSA-detected prostate cancer cases and 12,005 controls in the ProtecT trial. We developed a prostate cancer dietary index by incorporating three dietary factors most strongly associated with prostate cancer. Scores were computed to quantify adherence to the WCRF/AICR recommendations and the prostate cancer dietary index separately. Results: The prostate cancer dietary index score was associated with decreased risk of prostate cancer (OR per 1 score increment: 0.91, 95% CI: 0.84, 0.99; p-trend=0.04) but the WCRF/AICR index score was not (OR: 0.99, 95% CI: 0.94, 1.05; p-trend=0.82). There was no heterogeneity in association by prostate cancer stage (p=0.46) or grade (p=0.86). Greater adherence to recommendations to increase plant foods (OR per 0.25 index score increment: 0.94; 95% CI: 0.89, 0.99; p-trend=0.02) and tomato products (OR adherence vs. non-adherence: 0.82; 95% CI: 0.70, 0.97; p=0.02) were inversely associated with overall prostate cancer risk. Conclusions: Adherence to the prostate cancer-specific dietary recommendations was associated with decreased risk of prostate cancer. High intake of plant foods and tomato products in particular may help protect against prostate cancer. Impact: Meeting the WCRF/AICR recommendations alone is insufficient for prostate cancer prevention. Additional dietary recommendations should be developed.

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