bio360 · 2013/12/22
一项新研究证实了谚语“一天一苹果,医生远离我。”科学家利用数学模型推算出,如果全英国50岁以上的中老年人都能坚持每天吃一个苹果,则一年可减少 8500 例因心脏病或中风等心血管疾病引发的死亡。


日前,英国牛津大学的研究人员在新一期《英国医学杂志》(BMJ)上报告说,他们利用数学模型推算出,如果全英国50岁以上的中老年人都能坚持每天吃一个苹果,则一年可减少 8500 例因心脏病或中风等心血管疾病引发的死亡。

苹果富含矿物质和维生素,其营养价值早就为人熟知。此外,苹果所含的纤维、抗氧化剂和类黄酮均有助保护心血管健康。这个效果已经接近服用药物的效果。分析显示,如果这些中老年人每天服用他汀类降胆固醇药物,一年也不过减少 9400 例相关死亡。

领导这项研究的 Adam Piggs 表示,上述结果证明这句一百多年前的谚语至今仍有指导意义,看似微小的饮食改变就能给身体带来好处。但可惜的是,对于现代人每天至少应吃 5 种蔬菜水果的健康建议,却很少有人能真正做到。


  • A statin a day keeps the doctor away: comparative proverb assessment modelling study

    Objective To model the effect on UK vascular mortality of all adults over 50 years old being prescribed either a statin or an apple a day. Design Comparative proverb assessment modelling study. Setting United Kingdom. Population Adults aged over 50 years. Intervention Either a statin a day for people not already taking a statin or an apple a day for everyone, assuming 70% compliance and no change in calorie consumption. The modelling used routinely available UK population datasets; parameters describing the relations between statins, apples, and health were derived from meta-analyses. Main outcome measure Mortality due to vascular disease. Results The estimated annual reduction in deaths from vascular disease of a statin a day, assuming 70% compliance and a reduction in vascular mortality of 12% (95% confidence interval 9% to 16%) per 1.0 mmol/L reduction in low density lipoprotein cholesterol, is 9400 (7000 to 12 500). The equivalent reduction from an apple a day, modelled using the PRIME model (assuming an apple weighs 100 g and that overall calorie consumption remains constant) is 8500 (95% credible interval 6200 to 10 800). Conclusions Both nutritional and pharmaceutical approaches to the prevention of vascular disease may have the potential to reduce UK mortality significantly. With similar reductions in mortality, a 150 year old health promotion message is able to match modern medicine and is likely to have fewer side effects.

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