生物谷 · 2016/01/10



这项准则发表于国际杂志the British Journal of Pharmacology上,研究者Stephen Alexander博士表示,目前更新的准则是最先进的参考指南,其可以指导科学家们寻找并研究大量关键的药理学及治疗性的药物靶点;该指南将定量的药理学数据同大量的受体、离子通道、转运蛋白及酶类家族相结合,从而就可以为任何一名科学家提供新的研究领域来快速获取其所想要的药物靶点的相关数据信息。


  • The Concise Guide to PHARMACOLOGY 2015/16: Overview

    The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (, which provides more detailed views of target and ligand properties. The full contents can be found at This compilation of the major pharmacological targets is divided into eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.

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